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1 : Male
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First
visited our clinic at age 3 years and 9 months, First visit: February
1, 2003
Name of disease: Atopic dermatitis (AD); |
| Medical history:
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The
patient developed AD shortly after birth and occasionally
used topical steroids prescribed by a nearby doctor. When
the skin condition was exacerbated a year ago, the patient
was treated with various topical medications including Rinderon-VG
and Kindavate. He visited our clinic when treatment at other
hospitals failed to improve symptoms. Initial consultation:
Severe nummular eczema was present on the face, neck, trunk,
and limbs. Intense pruritus caused severe sleep disruption
at night. Scores: eczema score (ES): 4, pruritus score (IS):
4. Blood test: eosinophilis: 13.6%, IgE: 8 IU/ml.
Treatment progress: Oral forms of the sopora root compound
? 3 times daily at a dosage of 0.3g. Topical forms of the
sopora root compound (soap, liquid, and ointment) ? 2 to
3 times daily. Use of steroids was discontinued within one
week. Symptoms improved in 1 month and ES and IS dropped
to 2. Topical medication became almost unnecessary at 6th
month (ES: 1, IS: 1), and symptoms mostly cleared up at
12th month (ES: 0, IS: 0). Blood test: eosinophilis: 2.8%,
IgE: 5 IU/ml. No impairment of hepatorenal functions before
or after therapy. The dosage of oral medication was reduced
in half and therapy was terminated in June of 2004. In the
follow-up survey over the phone in March 2006, the patient
described his condition as good. |
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2 : Male
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First
visited our clinic at age 5, First visit: September 14, 2002
Name of disease: Atopic dermatitis, bronchial asthma |
| Medical history:
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The
patient developed infantile dermatitis around 4 months after
birth. Symptoms of dermatitis were later aggravated and
the patient was diagnosed with AD by a dermatologist. Treatment
with topical steroids was started and continued for some
time (Rinderon-VG once daily). At age 3, the patient developed
bronchial asthma, which is currently being treated. Initial
consultation: Severe erythema and dryness occurred on the
entire skin surface, accompanied by erosion and infiltration
in some areas. Thickening of skin and nummular eczema were
present on the trunk and limbs. Intense pruritus frequently
disrupted sleep at night. Scores: ES: 4, IS: 4. Blood test:
eosinophilis: 40.8%, IgE: 11400IU/ml.
Treatment progress: Oral forms of the
sopora root compound ? 3 times daily at a dosage of 0.5g.
Topical forms of the sopora root compound (soap, liquid,
and ointment) ? 3 times or more daily. Use of steroids was
gradually tapered off within 4 weeks. Symptoms improved
in 3 months and ES and IS dropped to 2. Symptoms of bronchial
asthma were also relieved and only one attack occurred during
the course of treatment. Scores at 6th month: ES: 1, IS:
1. Scores at 12th month: ES: 1, IS: 1. No asthma attack
was reported. Eosinophilis: 14.9%, IgE: 3520 IU/ml. No impairment
of hepatorenal functions before or after therapy. Treatment
was terminated at 18th month. Symptoms of AD recurred about
one year after the cessation of Chinese herb therapy (ES:
2, IS: 1).
Symptoms disappeared within 3 months of resuming the same
prescriptions.
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3 : Male
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First
visited our clinic at age 11, First visit: August 26, 2000
Name of disease: Atopic dermatitis, allergic rhinitis, bronchial
asthma |
| Medical history:
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The
patient developed AD and allergic rhinitis immediately after
birth, and bronchial asthma at age 3. Topical steroids were
used continuously for extended periods of time. Symptoms
of AD were exacerbated after steroid therapy was stopped
2 years ago. Treatment was changed to various non-steroid
medications, which proved to be unsuccessful. Initial consultation:
Erythema, thickening of skin, dermatitis, and desquamation
appeared on the entire skin surface, accompanied by erosion
and infiltration in some areas. Intense pruritus caused
severe sleep disruption at night. Scores: ES: 4, IS: 4.
Blood test: eosinophilis: 22.2%, IgE 16700 IU/ml.
Treatment progress: Oral forms of the sopora root compound
? 3 times daily at a dosage of 0.7g. Topical forms of the
sopora root compound (soap, liquid, and ointment) ? 3 times
or more daily. Symptoms improved in 3 months (ES: 2, IS:
2). Scores at 6th month: ES: 2, IS: 1. Scores at 12th month:
ES: 1, IS: 1. Eosinophilis: 10%, IgE: 4990 IU/ml. Scores
at 24th month: ES: 1, IS: 0, Eosinophilis: 7.4%, IgE: 5090
IU/ml. No impairment of hepatorenal functions before or
after therapy. Oral medication is administered once or twice
daily at a dosage of 1g. Topical medication is administered
intermittently. The patient¡Çs condition has been mostly
stable. |
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4 : Female
First
visited our clinic at age 47. First visit: September 26, 2003
Name of disease: Atopic dermatitis; |
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| Medical history:
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The
patient developed AD at age 5. Symptoms were relieved by
topical steroid treatment. The condition returned after
delivering a child at age 23. Hives also developed at that
time. Symptoms were alleviated by topical steroid treatment.
The effectiveness of steroids gradually diminished around
age 30. After the discontinuation of steroid treatment,
various non-steroid medications were tried without success.
The patient developed cataract in the right eye at age 41
(the condition is currently under observation). Initial
consultation: Severe erythema and dryness occurred on the
entire skin surface. Nummular eczema with severe inflammation
was present on the face, neck, limbs, and abdomen, accompanied
by erosion and infiltration. Pruritus levels were highest.
ES and IS: 4. Blood test: eosinophilis: 22%, IgE: 20 IU/ml.
Treatment progress: Oral forms ? 3 times daily at a dosage
of 1.5g. Topical forms ? 3 times daily. Scores at 1st month:
ES: 2, IS: 2. Scores at 3rd month: ES: 1, IS: 1.
The frequency and dosage of oral medication have been reduced
(twice daily at a dosage of 1g). Topical medication will
be terminated in one year and oral medication will be administered
at a dosage of 1 to 1.5g per day. The patient¡Çs skin is
in good condition (ES: 0, IS: 0-1). Eosinophilis: 5.5%,
IgE: 10 IU/ml. No impairment of hepatorenal functions before
or after therapy.
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5 : Female
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First
visited our clinic at age 22, First visit: January 16, 2003
Name of disease: Atopic
dermatitis, alopecia, bronchial
asthma |
| Medical history: |
The
patient developed AD at age 3, with coexisting alopecia
and bronchial asthma. After the onset of symptoms, topical
steroids were used to treat the condition until age 18.
Symptoms rapidly worsened after the cessation of steroid
therapy. Various folk remedies were tried, but symptoms
did not improve. Initial consultation: Extremely severe
erythema appeared on the skin, particularly noticeable on
the upper body. Dermatitis accompanied by erosion and infiltration
was also present. Scores: ES: 4, IS: 4. Eosinophilis: 21.3%,
IgE: 3760 IU/ml. Oral forms ? 3 times daily at a dosage
of 1.2g. Topical forms ? 3 to 6 times daily. Symptoms improved
in 3 months (ES: 1, IS: 1). Scores at 12th month: ES: 0,
IS: 0. Eosinophilis: 8.7%, IgE: 1460 IU/ml. Oral medication
was terminated and topical medication is applied as needed.
The patient¡Çs condition has been stable for the last three
years. |
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6 : Male
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First
visited our clinic at age 22, First visit: May 19, 2004, Name
of disease: Atopic dermatitis |
| Medical history: |
The
patient developed AD at age 3. Symptoms were exacerbated
after entering elementary school. Topical steroid treatment
was started, but symptoms were not completely controlled.
Beginning in the third grade, the patient began receiving
treatment as an inpatient at various hospitals. Symptoms
alternated between improvement and exacerbation during the
course of treatment. The condition was further aggravated
after the cessation of topical steroid therapy in February
2004. Initial consultation: Severe inflammation, erythema,
erosion, edema, and infiltration were observed on the skin,
particularly noticeable in the face. Pruritus was extremely
intense. Scores: ES: 3, IS: 4. Eosinophilis: 30%, IgE: 17600
IU/ml.
Oral forms ? 3 times daily at a dosage of 1.5g. Topical
forms ? same as above. Scores at 1st month: ES: 1, IS: 2.
Scores at 3rd month: ES: 1, IS: 1. The frequency and dosage
of oral medication were gradually tapered off (2 to 3 times
daily at a dosage of 1g). Scores: ES: 0, IS: 0-1. The patient¡Çs
skin is in good condition. Eosinophilis: 5.5%, IgE: 13900
IU/ml. No impairment of hepatorenal functions before or
after therapy. Treatment was terminated at 6th month at
the patient¡Çs request. |
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7 : Female
First
visited our clinic at age 34,
First visit: July 27, 2001,
Name of disease: Atopic dermatitis
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| Medical history: |
The
patient developed AD when in elementary school, and topical
steroids were used to control symptoms. The condition was
exacerbated around age 18, at which time symptoms became
refractory to topical steroids. Protopic therapy and various
folk remedies were tried, but symptoms did not improve.
Initial consultation: Severe erythema, thickening of skin,
and dryness appeared on the entire skin surface. Lichenification
and nummular eczema were observed in some areas, accompanied
by fissure, erosion, and infiltration. Pruritus was extremely
intense. Scores: ES: 4, IS: 4. Eosinophilis: 24.9%, IgE:
19000 IU/ml. Oral forms ? 3 times daily at a dosage of 1.2g.
Topical forms ? 3 to 6 times daily. Symptoms improved in
6 months. Scores: ES: 2, IS: 2. Symptoms mostly cleared
up at 12th month and ES and IS dropped to 1. Eosinophilis:
4.9%, IgE: 9949.9 IU/ml. At 24th month: ES: 1, IS: 1. Eosinophilis:
3%, IgE: 2600. Oral and topical medication is currently
administered intermittently. |
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8 : Female
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First
visited our clinic at age 74, First visit: June 5, 2003, Name
of disease: Atopic dermatitis |
| Medical history: |
The
patient developed AD 18 years ago. After using topical steroids
for 7 years, the patient decided to discontinue steroid
therapy, which resulted in rapid exacerbation of symptoms.
Oral antihistamines, topical forms of Protopic, and various
folk medicines were tried, but symptoms did not improve.
Initial consultation: Erythema, thickening of skin, and
severe dryness occurred on the entire skin surface. Lichenification
and nummular eczema were observed in some areas, accompanied
by fissure, erosion, and infiltration. The patient also
experienced extremely intense pruritus and occasional diarrhea.
Scores: ES: 4, IS: 4. Eosinophilis: 26.1%, IgE: 17900 IU/ml.
Oral forms ? 3 times daily at a dosage of 0.5g. Topical
forms ? 3 to 6 times daily. Protopic therapy was gradually
tapered off within a month. Symptoms improved at 6th month
of therapy and ES and IS dropped to 2. Skin symptoms almost
completely disappeared at 12th month.
Scores: ES: 1, IS: 0. Eosinophilis: 10.2%, IgE: 9980 IU/ml.
At 24th month: ES: 1, IS: 0. Oral medication is administered
in the same manner as above and topical medication is administered
intermittently. |
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